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Study identifier: NCT07718048 Synced from ClinicalTrials.gov · July 28, 2026
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Acute Effects of MCT Formulations on Beta-Hydroxybutyrate Response, Lipid Profile, and Glucose Levels in Healthy Adults

Condition: Ketone Body · Lipid Metabolism · Glucose Response  ·  Sponsor: University of Milan

PhaseNA
Planned participants12
Who can joinAll sexes, 18 Years to 40 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to evaluate the effects of medium-chain triglycerides (MCTs), delivered in different formulations, on beta-hydroxybutyrate response (as a marker of ketone body production), lipid metabolism, and glucose responses in healthy adults. The main questions it aims to answer are: Do MCTs influence beta-hydroxybutyrate responses, lipid metabolism, and glucose responses differently compared to long-chain triglycerides (LCTs)? Do different types of MCTs (natural sources containing C8 to C12 versus synthetic formulations containing only C8 and C10) lead to different beta-hydroxybutyrate, lipid, and glucose responses? Does the form in which MCTs are consumed (e.g., powders or incorporated into foods) influence beta-hydroxybutyrate production, lipid metabolism, and glucose responses? Researchers will compare five different lipid formulations to evaluate their effects on postprandial beta-hydroxybutyrate concentrations, blood lipid levels, and glucose. Participants will: Consume five different test products on separate study visits. Provide blood samples for up to five hours after each intake for metabolic measurements.

This description comes directly from the study's public registry record.

Talk to the study team

Alessandro Leone  ·  00390250316652  ·  alessandro.leone1@unimi.it

Always discuss trial participation with your own doctor first.

Locations (1)

International Center for the Assessment of Nutritional Status and the development of Dietary Intervention Strategies (ICANS-DIS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of MilanMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07718048