Condition: Adults · Acute Respiratory Tract Infection · Antibiotic Prescriptions · Sponsor: Oxford University Clinical Research Unit Indonesia
Antimicrobial resistance (AMR) has emerged as one of the most pressing global health challenges of the 21st century, particularly Indonesia is projected to be among the five nations globally with the highest percentage increase in antimicrobial consumption by 2030. Primary care settings represent the most critical implementation point for addressing inappropriate antibiotic use. ARTI constitutes the most common indication for antibiotic prescribing in primary care, yet much of this prescribing is inappropriate. The high frequency of inappropriate antibiotic prescribing for ARTI is particularly problematic because most of these infections are viral in nature and resolve spontaneously without antibiotic treatment. Studies across the Asia-Pacific region, including Indonesia, have documented antibiotic prescribing rates for upper respiratory tract infections ranging from 47% to 85%, indicating substantial overuse. C-reactive protein (CRP) point-of-care test (POCT) has emerged as a promising, evidence-based implementation to reduce inappropriate antibiotic prescribing for acute respiratory infections in a systematic review of studies conducted primarily in primary care settings of high- and middle-income countries. However, the efficacy and safety of CRP POCT implementation have not been evaluated in Indonesian primary care settings, where healthcare infrastructure, patient populations, test acceptability, and prescribing practices may differ significantly from countries where st…
This description comes directly from the study's public registry record.
Robert Sinto, MD, DPhil · +622123599099 · rsinto@oucru.org
Raph L Hamers, MD, PhD · +622123599099 · rhamers@oucru.org
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| Cengkareng Public Health Center | Jakarta, Indonesia | Recruiting |
| Kebayoran Lama Public Health Center | Jakarta, Indonesia | Enrolling By Invitation |
| Pulo Gadung Public Health Center | Jakarta, Indonesia | Recruiting |
| Jatinegara Public Health Center | Jakarta, Indonesia | Recruiting |
| Duren Sawit Public Health Center | Jakarta, Indonesia | Recruiting |
| Cakung Public Health Center | Jakarta, Indonesia | Recruiting |
| Cilincing Public Health Center | Jakarta, Indonesia | Recruiting |
| Koja Public Health Center | Jakarta, Indonesia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07717372