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Study identifier: NCT07715591 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

Condition: Cataract · Cataract (Post-operative Cataract Surgery Follow-up)  ·  Sponsor: University of California, Los Angeles

PhaseNA
Planned participants300
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This randomized controlled trial evaluates whether a standardized perioperative neuroplastic intervention: the STEIN Protocol (Strategies and Techniques for Enhancing Integration and Neuroplasticity), consisting of pain neuroscience education, guided imagery, and paced breathing, reduces intraoperative analgesic and anxiolytic requirements. Secondary outcomes include patient-reported pain, anxiety, satisfaction, and postoperative recovery following cataract surgery. Reduced intraoperative sedative and analgesic requirements may reflect improved patient comfort and autonomic regulation while minimizing medication-related adverse effects.

This description comes directly from the study's public registry record.

Talk to the study team

Shawn R Lin, MD, MS, MBA  ·  310-206-7955  ·  slin@jsei.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Stein Eye Institute - University of California Los AngelesLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07715591