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Study identifier: NCT07713550 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Added Value of Tissue or Liquid Biopsy NGS Profiling in Advanced Solid Tumor Treatment Decisions.

Condition: Advanced Solid Tumor Cancer · Primary CNS Tumors  ·  Sponsor: The Belgian Society of Medical Oncology

PhaseN/A
Planned participants550
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A total of 550 patients with metastatic solid tumors or primary CNS malignancy will be recruited on a first come first serve basis at one of the 14 participating centers : UZL, UZG, Imelda, ZAZ, AZ Klina, CHU Liège, GHdC, CHU UCL Namur, IJB, UZB, CUSL, UZA, VITAZ and Jessa Zh.. \> 500 patients with tissue available will undergo CGP centrally at UZ Leuven (Roche AVENIO Tumor Tissue CGP kits, Novaseq platform). \> 50 patients without tissue available will undergo liquid biopsy testing at Foundation Medicine (FoundationOne Liquid CDx). The sequencing data generated by UZ Leuven laboratory will then be further analysed (secondary and tertiary analysis) by one of the eight laboratories participating in the study: UZL, UZG, IJB, CUSL, IPG, UZA, Jessa zh. and CHU Liège.

This description comes directly from the study's public registry record.

Talk to the study team

Julie Maetens  ·  +32 2 642 54 90  ·  Julie.Maetens@sciensano.be

Gordana RaicevicToungouz  ·  +32 2 642 54 90  ·  Gordana.RaicevicToungouz@sciensano.be

Always discuss trial participation with your own doctor first.

Locations (14)

Institute Jules BordetAnderlecht, BelgiumRecruiting
ZASAntwerp, BelgiumRecruiting
ImeldaBonheiden, BelgiumRecruiting
AZ KlinaBrasschaat, BelgiumRecruiting
Universitaire Ziekenhuis AntwerpenEdegem, BelgiumRecruiting
UZ GentGhent, BelgiumRecruiting
GHDCGilly, BelgiumRecruiting
Jessa ZiekenhuisHasselt, BelgiumRecruiting
UZ BrusselJette, BelgiumRecruiting
UZ LeuvenLeuven, BelgiumRecruiting
CHU Liège Sart TilmanLiège, BelgiumRecruiting
CHU UCL NamurNamur, BelgiumRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07713550