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Study identifier: NCT07712029 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase II Study of Becotatug Vedotin Plus Pucotenlimab for Advanced Refractory Solid Tumors With EGFR-Positive

Condition: Advanced Refractory Solid Tumors · EGFR Gene Overexpression  ·  Sponsor: Tianjin Medical University Second Hospital

PhasePhase 2
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial evaluates the combination of Becotatug Vedotin (MRG003), an EGFR-targeting ADC, and Pucotenlimab (HX008), a PD-1 inhibitor, in patients with high EGFR expressing advanced refractory solid tumors. The study is designed to assess clinical efficacy and safety, building on a strong synergistic rationale and promising early-phase data.

This description comes directly from the study's public registry record.

Talk to the study team

Haitao Wang, Ph.D.  ·  +86-022-88321190  ·  peterrock2000@126.com

Lili Wang, Ph.D.  ·  +86-022-88321185  ·  wangliliaigang@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Tianjin Medical Unversity Second HospitalTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07712029