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Study identifier: NCT07708662 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Boosted Compression for Lower Limb Chronic Edema

Condition: Chronic Edema · Lymphedema  ·  Sponsor: Universiteit Antwerpen

PhaseNA
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care during the intensive treatment phase. Boosted compression involves thrice-daily re-application of a multicomponent short stretch compression bandage, aimed at enhancing the efficacy of compression therapy within edema treatment. Comparison: Comparison will be made between the experimental intervention (boosted compression) and the prevailing standard edema treatment, which adheres to the complex decongestive therapy as stipulated by healthcare services, utilizing a single daily application of compression bandage. Standard care is administered under the supervision of trained physical therapists, specialized in edema treatment. Outcome: Primary outcomes encompass the determination of: 1. the requisite number of treatment days to attain a non-pitting edema state during the intensive phase of edema treatment; and 2. the non-inferiority of boosted compression in maintaining reduced edema volume during the maintenance phase assessed at 1y of follow-up. Secondary outcomes encompass assessments of: Quality of Life, acceptance, and adherence to boosted compression, alongside evaluations of time and cost-effectiveness associated with its implementation.

This description comes directly from the study's public registry record.

Talk to the study team

Nick Gebruers, PT, PhD, Professor  ·  +32496184346  ·  nick.gebruers@uantwerpen.be

Always discuss trial participation with your own doctor first.

Locations (4)

Antwerp University HospitalEdegem, Antwerp, BelgiumRecruiting
University of AntwerpWilrijk, Antwerp, BelgiumRecruiting
University Hospital LeuvenLeuven, Brabant, BelgiumRecruiting
Ghent University HospitalGhent, East Flanders, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT07708662