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Study identifier: NCT07707063 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients

Condition: Periodontitis · Smokers · Non Smokers  ·  Sponsor: Military Hospital of Tunis

PhasePhase 4
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a randomized, controlled, split-mouth clinical trial designed to evaluate and compare the effectiveness of four different subgingival adjuncts used along side standard Scaling and Root Planning (SRP). This protocol is designed to be a standardized therapeutic model. The subgingival adjuncts are standardized, ensuring that the results are not operator dependent and can be replicated across any dental unit. The primary goal of this study is to evaluate the clinical efficacy of three distinct adjunctive strategies: Biological (I-PRF), Antiseptic : Povidone- iodine , Diode-Laser activation, compared to a Saline Control in the initial treatment of stage 2, 3 and stage 4 of the 2018 AAP/EFP periodontal classification.

This description comes directly from the study's public registry record.

Talk to the study team

Hela Jegham, DDS - Professor  ·  +21654241521  ·  hela.jegham@yahoo.fr

hedi chouchene, DDS  ·  +21652042177  ·  chouchanehadi76@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Military Hospital of Instruction of TunisTunis, Mont Fleury, TunisiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07707063