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Study identifier: NCT07705035 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DBC-664 in Adult Patients With Solid Tumors

Condition: Malignant Germ Cell Tumor · Lung Adenocarcinoma · Gastric/Esophageal/Gastroesophageal Junction (GEJ) Adenocarcinoma  ·  Sponsor: Duboce Biopharmaceuticals, Inc.

PhasePhase 1
Planned participants210
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

DBC-664-ONC-101 is a first-in-human Phase 1a/1b open-label, multicenter study to evaluate the safety, tolerability, PK, pharmacodynamic, and preliminary anti-tumor activity of DBC-664 in patients with endometrial cancer, ovarian cancer, and other advanced solid tumors . This study is divided into 2 parts: Phase-1a Dose Escalation (Part 1), and Phase-1b Dose Expansion (Part 2). In each part, patients who meet specific eligibility criteria will be enrolled.

This description comes directly from the study's public registry record.

Talk to the study team

Lisa Knapp  ·  +1 (650) 442-3367  ·  lknapp@tcglsoleil.com

Always discuss trial participation with your own doctor first.

Locations (3)

START MidwestGrand Rapids, Michigan, United StatesRecruiting
START New JerseyEast Brunswick, New Jersey, United StatesRecruiting
START New YorkLake Success, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07705035