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Study identifier: NCT07704658 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors

Condition: NSCLC (Non-small Cell Lung Cancer) · Thyroid Cancer · Solid Tumor Malignancies  ·  Sponsor: Rigel Pharmaceuticals

PhasePhase 4
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

An open-label drug-drug interaction study to evaluate the effects of pralsetinib (Gavreto) on the pharmacokinetics of a CYP450 probe substrate cocktail and, in female participants, a hormonal probe substrate, in participants with rearranged during transfection (RET) fusion- or mutation-positive solid tumors

This description comes directly from the study's public registry record.

Talk to the study team

Kay Patel  ·  (650) 624-1100  ·  kpatel@rigel.com

Jill DeFratis  ·  (650) 624-1100  ·  jdefratis@rigel.com

Always discuss trial participation with your own doctor first.

Locations (2)

Hospital Universitario San PedroLogroño, La Rioja, SpainRecruiting
Hospital Universitario HM SanchinarroMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07704658