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Study identifier: NCT07704554 Synced from ClinicalTrials.gov · July 29, 2026
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Dural Puncture Epidural (DPE) Technique: Efficacy and Safety Overview.

Condition: Labor Pain  ·  Sponsor: Ohio State University

PhaseN/A
Planned participants150
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Neuraxial techniques such as lumbar epidural and combined spinal-epidural (CSE) are the most effective methods for labor analgesia and are associated with high patient satisfaction. However, standard epidurals can have failure rates and may be difficult to reliably confirm correct placement. The dural puncture epidural (DPE) technique has been introduced to improve confirmation of epidural placement and potentially enhance analgesia. It involves identifying the epidural space, puncturing the dura with a spinal needle without injecting medication, confirming cerebrospinal fluid flow, and then placing the epidural catheter. While DPE may improve analgesia and drug spread, current evidence is limited and does not clearly demonstrate superiority over standard epidural techniques. At The Ohio State Wexner Medical Center, DPE is used routinely for labor epidurals. This observational study evaluates epidural failure rates and anesthesia provider confidence in performing DPE, while also collecting procedural details, patient characteristics, analgesic outcomes, and complications. Provider confidence is assessed using a 3-point scale along with factors influencing performance, and patient outcomes include pain relief, need for rescue dosing, and overall epidural effectiveness.

This description comes directly from the study's public registry record.

Talk to the study team

Goran Ristev  ·  6142938487  ·  goran.ristev@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Ohio State University Wexner Medical Center HospitalsColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07704554