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Study identifier: NCT07702461 Synced from ClinicalTrials.gov · July 29, 2026
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Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists

Condition: Obesity & Overweight · Diabetes (DM)  ·  Sponsor: Ohio State University

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study examines how adults who take a GLP-1 receptor agonist medication (such as semaglutide \[Ozempic, Wegovy, Rybelsus\], liraglutide \[Saxenda, Victoza\], or tirzepatide \[Mounjaro, Zepbound\]) perform resistance (strength) training before and after starting their medication. GLP-1 medications are being prescribed more and more often to help people manage type 2 diabetes and lose weight. These medications work well, but a known side effect is that people can lose lean (muscle) tissue along with fat. Losing muscle can make it harder to move, do everyday tasks, and stay strong as we age. Resistance training, things like lifting weights, using resistance bands, or doing push-ups and squats, is the most effective way to keep and build muscle. Yet most adults in the United States do not meet the recommended amount of resistance training, and very little is known about the resistance training habits of people who take GLP-1 medications. The purpose of this research is to systematically collect information from adults using GLP-1 medications so we can better understand: how often they do resistance training before and after starting the medication; what their sessions look like (frequency, duration, intensity, muscle groups); whether their resistance training is linked to how strong they feel and how well they can carry out daily activities; and what makes resistance training easier or harder while on a GLP-1 medication. Findings will help doctors, dietitians, exercise pro…

This description comes directly from the study's public registry record.

Talk to the study team

Madison L Kackley, PhD  ·  614-247-9650  ·  kackley.19@osu.edu

Sam Soufi, BS  ·  703-321-6784  ·  soufi.3@osu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Ohio State UniversityColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07702461