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Study identifier: NCT07701486 Synced from ClinicalTrials.gov · July 28, 2026
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A Study of More Frequent Dosing of VCN-01 Combined With Standard Chemotherapy in Patients With Newly Diagnosed Metastatic Pancreatic Cancer

Condition: Pancreas Cancer, Metastatic · Pancreas Cancer, Stage IV · Ductal Adenocarcinoma of the Pancreas  ·  Sponsor: Theriva Biologics SL

PhasePhase 1/Phase 2
Planned participants6
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if the new administration regimen of VCN-01, given together with the standard chemotherapy drugs gemcitabine and nab-paclitaxel (GnP), is safe and well tolerated. The behaviour of VCN-01 in the organism will be assessed, together with the possible benefits of this administration regimen. This study includes adults with newly diagnosed pancreatic ductal adenocarcinoma (PDAC) that has spread to other parts of the body (stage IV) and who have not received prior treatment for pancreatic cancer. Participants will receive three planned doses of VCN-01, given once every 56 days. Each dose of VCN-01 is followed one week later by two cycles of standard chemotherapy with gemcitabine and nab-paclitaxel. Participants will be monitored throughout the study for safety and side effects.

This description comes directly from the study's public registry record.

Talk to the study team

Manel Cascalló CEO, PhD  ·  +93936899365  ·  mcascallo@therivabio.com

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital 12 de OctubreMadrid, Madrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07701486