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Study identifier: NCT07700537 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Neural Mechanisms of Transcranial Direct Current Stimulation Targeting the Supplementary Motor Area for the Treatment of Subacute Post-stroke Aphasia

Condition: Post-stroke Aphasia  ·  Sponsor: The First Affiliated Hospital of Anhui Medical University

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study aims to investigate the efficacy of transcranial direct current stimulation (tDCS) in patients with post-stroke aphasia (PSA) and to explore its potential neural mechanisms. The study will recruit PSA patients and provide them with 14 tDCS sessions over 7 days, along with speech therapy. Language Behavior Scale scores and resting-state functional MRI scans will be collected before and after the intervention. In addition, a retrospective comparison will be conducted of language function and resting-state fMRI changes in a group of PSA patients who received only speech therapy; these patients did not undergo any physical intervention but received only speech therapy. Changes in Language Behavior Scale scores and functional connectivity (FC) before and after treatment in the speech therapy-only group will be analyzed and compared with those in the tDCS intervention group.

This description comes directly from the study's public registry record.

Talk to the study team

Jian Guan  ·  +86-19810696998  ·  1003935828@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

transcranial direct current stimulation (tDCS)Hefei, Anhui, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07700537