Condition: Nicotine Dependence · Sponsor: University of Southern California
Oral nicotine pouches (ONPs) are non-combustible nicotine products that may reduce cigarette craving and smoking cue-induced brain activity, supporting their potential as harm-reduction tools for adults who smoke cigarettes. This within-subject, repeated-measures study will evaluate the acute effects of a single 6 mg oral nicotine pouch on subjective craving and prefrontal neural responses to smoking-related cues using functional near-infrared spectroscopy (fNIRS). Participants will complete assessments before and after nicotine pouch administration following overnight nicotine abstinence to characterize changes in craving and neural cue reactivity.
This description comes directly from the study's public registry record.
USC Nicotine and Tobacco Studies · 213-821-0807 · USCONPStudy@gmail.com
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| University of Southern California - 3641 Watt Way (HNB B22) | Los Angeles, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07698470