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Study identifier: NCT07690345 Synced from ClinicalTrials.gov · July 28, 2026
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Fungal Status and Prognosis in ABPA

Condition: ABPA · Allergic Bronchopulmonary Aspergillosis · Allergic Bronchopulmonary Aspergillosis (ABPA)  ·  Sponsor: Qianfoshan Hospital

PhaseN/A
Planned participants114
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This multicenter bidirectional cohort study aims to investigate the clinical characteristics and prognostic outcomes of patients with allergic bronchopulmonary aspergillosis (ABPA) stratified by fungal microbiological status in sputum or bronchoalveolar lavage fluid (BALF). Patients diagnosed with ABPA according to the ISHAM 2024 criteria will be classified into fungal-positive and fungal-negative groups based on results from fungal culture, galactomannan (GM) testing, and metagenomic next-generation sequencing (mNGS) of sputum or BALF samples. The study will compare baseline clinical features, laboratory findings, radiological characteristics, treatment response, and long-term outcomes, including acute exacerbation rate and time to first exacerbation, between the two groups. All participants will be followed for up to 12 months with serial clinical and laboratory assessments.

This description comes directly from the study's public registry record.

Talk to the study team

Qian Qi, Dr.  ·  +86 13706380314  ·  qiqianqlh@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Respiratory, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, #16766, Jingshi Road, Jinan City, Shandong Province, ChinaJinan, Shandong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07690345