Condition: STEMI - ST Elevation Myocardial Infarction · Sponsor: Oxford University Hospitals NHS Trust
The CAPTURE AMI trial is an investigator-initiated, single-centre, two-arm, randomised controlled trial. Patients aged ≥ 18 years who present with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) will be enrolled after angiographic evidence of a high thrombus burden (TIMI thrombus grade ≥ 4) and meeting the inclusion criteria laid out in section 9.2 will be 1:1 randomised to receive either standalone PCI (Arm 1) or adjunct sustained mechanical thrombectomy + PCI (Arm 2). The CAPTURE AMI study will enrol specifically patients with: A. Evidence of high thrombus burden on coronary angiography (TIMI thrombus grade ≥ 4) B. Culprit in an artery with a diameter of 3.0 mm or more. The trial is designed to evaluate the efficacy of sustained mechanical thrombectomy versus standalone PCI in patients with a large thrombus burden assessed angiographically, with a pre-stent thrombus burden (%) as the primary imaging endpoint.
This description comes directly from the study's public registry record.
Giovanni Luigi De Maria, MD · +44 18655 528364 · GiovanniLuigi.DeMaria@ouh.nhs.uk
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| Oxford Heart Centre - John Radcliffe Hospital | Oxford, Oxfordshire, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07687576