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Study identifier: NCT07682896 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease

Condition: Graves' Disease  ·  Sponsor: Yarrow Bioscience, Inc.

PhasePhase 2
Planned participants232
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being conducted to look at the effect YB-101 has on thyroid function. This study will also evaluate how safe and well tolerated YB-101 is and how it is distributed through the body. The study consists of a part 1, blinded treatment period, and a part 2 double-blinded treatment period. Participants will receive YB-101 or Placebo subcutaneously. Participants who participate in Part 1 can not participate in Part 2. Participants will complete 34-39 in-clinic visits in Part 1 or Part 2 over an approximate 40 week period.

This description comes directly from the study's public registry record.

Talk to the study team

Victoria Lacasse, MD  ·  469-278-6161  ·  VL@YarrowBioscience.com

Always discuss trial participation with your own doctor first.

Locations (28)

Site 112Gilbert, Arizona, United StatesRecruiting
Site 130Phoenix, Arizona, United StatesNot Yet Recruiting
Site 121La Mesa, California, United StatesNot Yet Recruiting
Site 103Sacramento, California, United StatesNot Yet Recruiting
Site 111San Francisco, California, United StatesNot Yet Recruiting
Site 105Torrance, California, United StatesNot Yet Recruiting
Site 109Miami Lakes, Florida, United StatesRecruiting
Site 115Palm Harbor, Florida, United StatesNot Yet Recruiting
Site 123Sarasota, Florida, United StatesNot Yet Recruiting
Site 118Macon, Georgia, United StatesRecruiting
Site 122Bowling Green, Kentucky, United StatesNot Yet Recruiting
Site 126Flint, Michigan, United StatesNot Yet Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07682896