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Study identifier: NCT07679893 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 2 Clinical Trial of MNKD-201 (Nintedanib Dry Powder Inhalation) in Patients With Idiopathic Pulmonary Fibrosis

Condition: Idiopathic Pulmonary Fibrosis · Idiopathic Pulmonary Fibrosis (IPF)  ·  Sponsor: Mannkind Corporation

PhasePhase 2
Planned participants210
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

This trial is a randomized, double-blind, placebo-controlled study evaluating the safety and preliminary efficacy of inhaled Nintedanib Dry Powder Inhalation (DPI) in adults with idiopathic pulmonary fibrosis (IPF). Participants are randomized to receive either 2 mg QID, 4 mg BID, or matching placebo for 12 weeks, followed by a 24-week open-label extension in which all participants receive active treatment. The primary focus is on safety-particularly bronchospasm events, lung function changes (FEV1, FEV1/FVC), and adverse event rates and assessing the effectiveness of nintedanib DPI in treating IPF.

This description comes directly from the study's public registry record.

Talk to the study team

Wassim Fares, MD, SVP, Therapeutic Area Head, Orphan Lung Disease, MD  ·  203-796-3407  ·  wfares@mannkindcorp.com

Always discuss trial participation with your own doctor first.

Locations (1)

Trial Management Group IncWindsor, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07679893