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Study identifier: NCT07677631 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Emotional Allodynia Questionnaire (AEQ) in Fibromyalgia (PEARL)

Condition: Fibromyalgia · Chronic Pain · Nociplastic Pain  ·  Sponsor: University of Bari

PhaseN/A
Planned participants423
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The Emotional Allodynia Questionnaire (AEQ) is an 11-item self-report instrument that measures disproportionate emotional reactivity to low-intensity interpersonal cues(perceived unresponsiveness, exclusion, loss of reciprocity), a pattern termed emotional allodynia. It was preliminarily validated in a single-center fibromyalgia sample. PEARL (validation phase) is a multicenter, prospective, observational psychometric validation study that (1) replicates the internal structure and convergent validity of the AEQ in an independent fibromyalgia sample, (2) tests its known-groups (discriminative) accuracy in separating fibromyalgia from non-fibromyalgia chronic pain of defined nociceptive or neuropathic origin, expressed as the area under the ROC curve (AUC), and (3) assesses test-retest reliability. There is no intervention.

This description comes directly from the study's public registry record.

Talk to the study team

Alberto Corriero, MD, PhD  ·  +39 3280072443  ·  alberto.corriero@gmail.com

Always discuss trial participation with your own doctor first.

Locations (5)

Pain Unit, Policlinico di Bari, University of Bari Aldo Moro (coordinating center)Bari, ItalyRecruiting
Anesthesia and Pain Therapy Unit, IRCCS AOSP di Bologna, Policlinico S. Orsola-MalpighiBologna, ItalyNot Yet Recruiting
Department of Medical Sciences and Public Health, University of CagliariCagliari, ItalyNot Yet Recruiting
Department of Women, Child and General and Specialized Surgery, University of Campania Luigi VanvitelliNaples, ItalyNot Yet Recruiting
Department of Surgery, Dentistry, Pediatrics and Gynecology, University of VeronaVerona, ItalyNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07677631