Condition: Gastric Cancer · Colorectal Cancer · Breast Cancer · Sponsor: Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo
This is a prospective observational cohort study conducted at Fundación CTIC in Bogotá, Colombia. It characterizes the oral, fecal and intratumoral microbiome of Colombian adults with advanced solid tumors (gastric, colorectal, breast, cervical and head-and-neck cancer) who receive first-line immunotherapy as standard of care, and compares them with healthy volunteers. Using multi-omics (HiFi metagenomics, 16S, tumor RNA-Seq and untargeted metabolomics), the study aims to identify microbial signatures associated with treatment response and survival, building the initial Colombian cohort of a Cancer Microbiome Atlas with Latin American projection.
This description comes directly from the study's public registry record.
Andrés F Cardona, MD, MSc, PhD, MBA · +573016348173 · acardona@fctic.org
Liliana Gutiérrez, RN, MSc · +573003768158 · lgutierrez@fctic.org
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| Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo | Bogotá, Bogota D.C., Colombia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07676461