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Study identifier: NCT07676370 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PROV-MESH: Prophylactic Ovarian Cancer MESH

Condition: Ovarian Cancer  ·  Sponsor: Hospital Vall d'Hebron

PhaseNA
Planned participants152
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Incisional hernia is a common complication after midline laparotomy and may significantly impact quality of life, morbidity, and healthcare costs. Patients undergoing cytoreductive surgery for ovarian cancer are considered at increased risk due to extensive surgical procedures, nutritional status, and exposure to systemic treatments. This prospective randomized clinical trial aims to evaluate whether prophylactic mesh placement during abdominal wall closure reduces the incidence of incisional hernia compared with conventional fascial closure in women undergoing cytoreductive surgery for ovarian cancer through a midline laparotomy. To control for the potential effect of negative pressure wound therapy (NPWT) on surgical site infection, participants will also be randomized to receive NPWT or standard wound dressing, resulting in four treatment arms.

This description comes directly from the study's public registry record.

Talk to the study team

Jose Luis Sánchez Iglesias, MD PhD  ·  +34 932746000  ·  jlsanig@yahoo.es

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Universitario Vall d'HebronBarcelona, Barcelona, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07676370