Condition: Type 2 Diabetes · Insulin Sensitivity/Resistance · Cognition · Sponsor: Rutgers, The State University of New Jersey
About 6.5 million adults in the United States who are 65 or older have dementia. While the exact cause of dementia is not known, it may be due to changes in the brain. Further, risk may be higher when the brain does not respond to insulin. Indeed, brain insulin resistance has emerged as a pathologic factor affecting memory, executive function as well as systemic glucose control. Regular aerobic exercise may help reduce the risk of dementia by increased blood flow to the brain and help the brain respond better to insulin. In addition, giving insulin through a nose spray (called intranasal insulin) may also help with thinking and memory. However, it is unknown if using both exercise and intranasal insulin is best for the brain.
This description comes directly from the study's public registry record.
Steven K Malin, PhD · 848-932-7540 · steven.malin@rutgers.edu
Emily M Heiston, PhD · 848-932-7540 · emily.heiston@rutgers.edu
Always discuss trial participation with your own doctor first.
| Robert Wood Johnson University Hospital Clinical Research Center | New Brunswick, New Jersey, United States | Recruiting |
| Institute for Food, Nutrition, and Health | New Brunswick, New Jersey, United States | Recruiting |
| Rutgers University Loree Gymnasium | New Brunswick, New Jersey, United States | Recruiting |
| Center for Advanced Human Brain Imaging Research | Piscataway, New Jersey, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07675499