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Study identifier: NCT07674732 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Nodal-Region Sparing Short-Course RT With Chemo-PD-1/Bevacizumab vs. Short-Course RT With Chemotherapy as TNT in pMMR/MSS Locally Advanced Rectal Cancer

Condition: Short-course Radiotherapy Plus Chemotherapy · Nodal-Region Sparing Short-Course Radiotherapy Followed by Sequential Chemotherapy With PD-1 Monoclonal Antibody and Bevacizumab  ·  Sponsor: Dechang Diao

PhasePhase 2
Planned participants76
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Safety and efficacy of Nodal-Region Sparing Short-Course Radiotherapy Followed by Sequential Chemotherapy With PD-1 Monoclonal Antibody and Bevacizumab versus Short-course Radiotherapy plus Chemotherapy as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer. Complete Response (CR) Rate of Nodal-Region Sparing Short-Course Radiotherapy Followed by Sequential Chemotherapy With PD-1 Monoclonal Antibody and Bevacizumab versus Short-course Radiotherapy plus Chemotherapy as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Dechang Diao, Dr  ·  13416119782  ·  diaodch3@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sixth Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07674732