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Study identifier: NCT07674264 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD

Condition: Parkinson Disease · Parkinsonism  ·  Sponsor: University of Florida

PhaseNA
Planned participants32
Who can joinAll sexes, 40 Years to 75 Years
Healthy volunteersNo

About this study

Parkinsonism impairs upper airway and axial motor control, leading to disordered breathing, reduced speech volume, and ineffective cough. Symptoms are poorly addressed by current therapies. This randomized pilot trial tests whether a single session of acute intermittent hypercapnic hypoxia (AIHH) or hypercapnic normoxia (AIHN) improves upper airway and axial motor function in Parkinsonism, and explores biomarker correlates of intervention responsiveness.

This description comes directly from the study's public registry record.

Talk to the study team

Michlela Mir, CCC-SLP, PhD  ·  352-273-6095  ·  michela.mir@ufl.edu

Alysha Bogard, PhD  ·  3038279875  ·  abogard@ufl.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of FloridaGainesville, Florida, United StatesRecruiting
Norman Fixel Institute for Neurological DiseasesGainesville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07674264