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Study identifier: NCT07673627 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis

Condition: AChR-Ab Seropositive Generalized Myasthenia Gravis · Myasthenia Gravis (MG) · MG - Myasthenia Gravis  ·  Sponsor: argenx

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is part of the ADAPT Forward platform study (NCT07294170). ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects and improve their quality of life. The aim of this ISA2 is to investigate the effects of empasiprubart in participants with AChR-Ab seropositive generalized myasthenia gravis (gMG). The ADAPT Forward master protocol is registered on https://clinicaltrials.gov/study/NCT07294170 More information can be found here: https://clinicaltrials.argenx.com/adaptforward2

This description comes directly from the study's public registry record.

Talk to the study team

Sabine Coppieters, MD  ·  857-350-4834  ·  clinicaltrials@argenx.com

Always discuss trial participation with your own doctor first.

Locations (2)

Visionary Investigators NetworkMiami, Florida, United StatesRecruiting
Erlanger Health SystemChattanooga, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07673627