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Study identifier: NCT07673328 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal

Condition: Lower-limb Orthoses · Osteoarthritic Knee Pain · Osteoarthritis (OA) of the Knee  ·  Sponsor: University of Michigan

PhaseNA
Planned participants65
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersYes

About this study

The overall goal of this project is to establish a novel design and control paradigm for modular, partial-assist powered orthoses (exoskeletons) to enhance voluntary lower-limb motion and manage pain in broad patient populations. Building upon a previous study period that addressed weakness from advanced age or muscle fatigue, this current period extends the technology to novel powered unloader orthoses designed to manage knee osteoarthritis (OA) pain. The investigators hypothesize that by providing 15-30% of biological joint torque, these motorized devices can reduce muscular contributions to painful loads on the joint's surfaces during activities of daily living (ADLs). The project aims to develop a task-agnostic, neural network-based controller and establish the feasibility of reducing knee pain and muscle effort in individuals with multi-compartment knee osteoarthritis.

This description comes directly from the study's public registry record.

Talk to the study team

Emily Klinkman  ·  734-763-1156  ·  emilykk@umich.edu

Robert Gregg  ·  734-763-1156  ·  rdgregg@umich.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Rehab LabAnn Arbor, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07673328