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Study identifier: NCT07671963 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Bone Substitutes and NIPSA in Intrabony Periodontal Defects: A Randomized Controlled Trial

Condition: Periodontitis (Stage 3) · Minimally Invasive Surgical Procedures · Bone Substitutes  ·  Sponsor: University of Belgrade

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

This multicenter randomized controlled clinical trial aims to compare the clinical, radiographic, microbiological and molecular outcomes of two collagenated xenogeneic bone substitutes (GTO® and GenOs®) used in combination with the Non-Incised Papilla Surgical Approach (NIPSA) for the treatment of intrabony periodontal defects. The study will evaluate whether differences exist between the two biomaterials with respect to clinical attachment gain, defect resolution, wound healing and biological markers of regeneration.

This description comes directly from the study's public registry record.

Talk to the study team

Iva Z Milinkovic, DDS, PhD  ·  +381113629201  ·  iva.milinkovic@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Department of Periodontology, School of Dental Medicine, University of Cagliari Cittadella Universitaria di Monserrato Monserrato (CA), ItalyCagliari, Italy, ItalyRecruiting
Department of Periodontology and Research Implant Center, School of Dental Medicine, University of BelgradeBelgrade, SerbiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07671963