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Study identifier: NCT07671651 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in Children

Condition: Dental Caries · Early Caries Lesion  ·  Sponsor: Neslihan Atmaca

PhaseNA
Planned participants80
Who can joinAll sexes, 6 Years to 14 Years
Healthy volunteersNo

About this study

Initial caries lesions can be managed using non-invasive treatment approaches that promote remineralization and prevent lesion progression. Ozone therapy has been suggested as an adjunctive treatment because of its antimicrobial properties and its potential to enhance remineralization. This randomized controlled clinical trial aims to evaluate the effect of ozone therapy on the remineralization of initial caries lesions in children. Participants will be randomly assigned to receive either ozone therapy followed by application of a remineralizing gel or application of the remineralizing gel alone. Changes in lesion status will be assessed over time using clinical and optical evaluation methods. The results of this study may contribute to the development of evidence-based minimally invasive approaches for the management of early caries lesions in pediatric patients.

This description comes directly from the study's public registry record.

Talk to the study team

Neslihan Atmaca, Doctor of Dental Surgery  ·  +905458314053  ·  nsltmc@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Marmara Universty School of DentistryIstanbul, Maltepe, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07671651