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Study identifier: NCT07670416 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes

Condition: Obesity · Overweight · Type 2 Diabetes Mellitus (T2DM)  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA) being developed for chronic weight management, as an adjunct to a reduced-calorie diet and increased physical activity in participants without Type 2 diabetes mellitus (T2DM) who have obesity or overweight with at least one weight-related comorbidity, and in participants with T2DM who have obesity or overweight.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: YC46401 https://forpatients.roche.com No attachments to email below.  ·  888-662-6728 (U.S. Only)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (12)

Yan'an University Xianyang HospitalXianyang, Shaanxi, ChinaRecruiting
The First Affiliated Hospital of Ningbo University(Ningbo First Hospital)Ningbo, Zhejiang, ChinaRecruiting
Peking University People's HospitalBeijing, ChinaRecruiting
Jinan Central HospitalJinan, ChinaRecruiting
Hebei Petro China Central HospitalLangfang, ChinaRecruiting
Luoyang Third People's HospitalLuoyang, ChinaRecruiting
Shanghai Tenth People's HospitalShanghai, ChinaRecruiting
Shanghai East HospitalShanghai, ChinaRecruiting
Tongren Hospital, Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, ChinaRecruiting
Shanghai Fifth People's Hospital Affiliated to Fudan UniversityShanghai, ChinaRecruiting
Hebei Medical University - The Second HospitalShijiazhuang, ChinaRecruiting
Zibo Municipal Hospital.Zibo, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07670416