Condition: Malaria, Falciparum · Sponsor: GlaxoSmithKline
This study aims to evaluate whether GSK3772701 alters the pharmacokinetics (PK) of midazolam (MDZ), a standard probe substrate for the CYP3A4 enzyme. The findings are planned to be used to determine whether GSK3772701 acts as an inducer and/or inhibitor of CYP3A4 and will help guide recommendations for safe co-administration with CYP3A4 substrates.
This description comes directly from the study's public registry record.
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Source record: clinicaltrials.gov/study/NCT07670377