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Study identifier: NCT07668557 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Anti-CD33-CLL1 CAR-T Cells (ICG415) for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia

Condition: Acute Myeloid Leukemia (AML)  ·  Sponsor: iCell Gene Therapeutics

PhasePhase 1
Planned participants18
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This single-arm, open-label phase I trial evaluates the safety and tolerability of ICG415, autologous CAR-T cells targeting CD33 and CLL1, in patients with relapsed or refractory acute myeloid leukemia (AML). Subjects receive lymphodepleting chemotherapy followed by autologous CAR-T infusion. The primary goal is to assess safety and preliminary anti-leukemic efficacy in patients failing standard AML therapies.

This description comes directly from the study's public registry record.

Talk to the study team

Yu Min  ·  +86 150 7902 9006  ·  625668742@qq.com

Li Fei  ·  +86 139 7003 8386  ·  yx021021@sina.com

Always discuss trial participation with your own doctor first.

Locations (2)

Jiangxi Provincial People's Hospital (Participating Site)Nanchang, Jiangxi, ChinaRecruiting
The First Affiliated Hospital of Nanchang University (Lead Site)Nanchang, Jiangxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07668557