Condition: Pulmonary Hypertension · Pulmonary Arterial Hypertension · Right Ventricular Function · Sponsor: Istanbul University - Cerrahpasa
The MIRROR-PAH is a single-center, prospective, observational cohort study evaluating the incremental value of multimodality imaging-derived right ventricular characteristics for risk stratification in patients with Group 1 pulmonary arterial hypertension (PAH). The study aims to determine whether incorporation of echocardiographic and cardiac magnetic resonance (CMR)-derived right ventricular parameters into established non-invasive risk assessment models results in risk reclassification and improves identification of patients at risk for short-term clinical worsening. Adult patients with established Group 1 PAH undergoing routine follow-up and with available right heart catheterization (RHC) and CMR data will be consecutively enrolled. Clinical, laboratory, echocardiographic, and follow-up data will be prospectively collected over a 6-month period. Associations between multimodality imaging findings, invasive hemodynamic measurements, risk classification, and short-term clinical outcomes will be evaluated.
This description comes directly from the study's public registry record.
Aybüke Geylan, MD · +905061258579 · aybukegeylan@gmail.com
Barış Güven, MD · +905321137507 · guvenbariss@gmail.com
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| Istanbul University Cerrahpasa Institute of Cardiology | Istanbul, Turkey (Türkiye) | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07667673