Condition: Patients Undergoing Orthopedic Hip Surgery Under Spinal Anesthesia · Orthopedic Hip Sugery in Eldely Patients · Sponsor: Sohag University
This prospective randomized double-blinded clinical trial aims to compare the efficacy and hemodynamic effects of prophylactic norepinephrine infusion versus phenylephrine infusion for prevention of spinal anesthesia-induced hypotension in elderly patients undergoing elective orthopedic hip surgery under subarachnoid block. Sixty-two patients aged 60 years or older will be randomly assigned into two equal groups to receive either norepinephrine infusion (8 µg/min) or phenylephrine infusion (100 µg/min) immediately after spinal anesthesia. The primary outcome is the mean heart rate during vasopressor infusion, while secondary outcomes include incidence of hypotension, severe hypotension, bradycardia, reactive hypertension, intraoperative fluid requirements, blood loss, transfusion requirements, and postoperative nausea and vomiting. Hemodynamic parameters will be monitored throughout surgery to evaluate the safety and effectiveness of both vasopressor strategies.
This description comes directly from the study's public registry record.
Ahmed Abdelhamed Faress, Resident · 01065080913 · drahmedfaress23896@gmail.com
Fawzy Abbas Badawy, Professor
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| Sohag university hospital | Sohag, Egypt | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07662408