Condition: Alzheimer Disease (AD) · Mild Cognitive Impairment (MCI) · Sponsor: Boston University Charles River Campus
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a nearly threefold higher rate of falls compared to neurotypical older adults. There is an urgent need for fall prevention interventions tailored to the unique deficits of individuals with AD. Converging evidence suggests that interventions aiming to reduce fall risk in AD should target both gait and cognition. Rhythmic music interventions, such as Rhythmic Auditory Stimulation (RAS) can harness global brain activation and auditory-motor entrainment to facilitate high-intensity exercise to alleviate AD-related neurocognitive and gait dysfunction. This study aims to assess the neural correlates of gait dysfunction in people with AD, evaluate if baseline neurocognitive impairment is predictive of the effects of RAS, and evaluate RAS benefits for individuals with AD.
This description comes directly from the study's public registry record.
Regina Sloutsky, PT, DPT, PhD · 617-500-3645 · reginas@bu.edu
Louis N Awad, PT, DPT, PhD · 617-500-3645 · louawad@bu.edu
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| Boston University Neuromotor Recovery Laboratory | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07659964