Condition: Diffuse Large B-cell Lymphoma (DLBCL) · Cardiotoxicity · Lymphoma · Sponsor: Beth Israel Deaconess Medical Center
This trial is to evaluate if dexrazoxane is safer and more effective than liposomal doxorubicin in preventing heart failure events in participants with diffuse large B-cell lymphoma (DLBCL) undergoing either standard of care R-CHOP or pola-R-CHP treatment regiments. The names of the study drugs involved in this study are: * Dexrazoxane (a type of Topoisomerase II Inhibitor) * Liposomal Doxorubicin (a type of Topoisomerase II Inhibitor) * Standard of care R-CHOP treatment regimen (Cyclophosphamide, doxorubicin, vincristine, prednisone, rituximab) * Standard of care pola-R-CHP treatment regimen: Cyclophosphamide, doxorubicin, polatuzumab vedotin-piiq, prednisone, rituximab
This description comes directly from the study's public registry record.
Jenica Upshaw, MD, MSc · (617) 667-8800 · jupshaw@bidmc.harvard.edu
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| Beth Israel Deaconess Medical Center | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07654426