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Study identifier: NCT07654166 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tissue Adhesive Versus Sutures in Oral Biopsy Closure

Condition: Mouth Neoplasms  ·  Sponsor: Damascus University

PhaseNA
Planned participants28
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Excisional biopsies are commonly performed in the oral mucosa, and proper wound closure and hemostasis are critical for the success of the surgical procedure. Suturing remains the gold standard for closing surgical incisions; however, it has several drawbacks, including being time-consuming and requiring technical skill for proper placement. In addition, access to posterior areas of the oral cavity can be challenging. Suturing may also cause patient discomfort during needle penetration of tissues and can serve as a potential pathway for microbial contamination. Therefore, this randomized controlled clinical trial aims to evaluate one of the latest tissue adhesives from the cyanoacrylate group (PeriAcryl 90 HV) compared to conventional surgical sutures (Nylon 4-0) for wound closure following oral excisional biopsies. A total of 28 patients with oral fibroma will be randomly assigned to either the tissue adhesive group or the suture group (14 patients per group).

This description comes directly from the study's public registry record.

Talk to the study team

Nour J Ibrahim, DDS _ MSc student  ·  +963959800513  ·  nouribrahim649@gmail.com

Omar H Hamadah, Professor  ·  +963940705554  ·  Omar.hamadah@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Damascus University ,Department of Oral Medicine, Faculty of DentistryDamascus, Mazzh, SyriaRecruiting

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Source record: clinicaltrials.gov/study/NCT07654166