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Study identifier: NCT07652580 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma

Condition: Non-Hodgkin Lymphoma · Lymphoma Non-Hodgkin · B-cell Lymphoma  ·  Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

PhaseN/A
Planned participants300
Who can joinAll sexes, 4 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether specific exposures and germline variants are associated with B-cell NHL subtype, immune dysfunction, and clinical outcomes. Participants will complete exposure and medical-history surveys, provide biospecimens for immune and genomic testing, and may be followed annually for up to 3 years.

This description comes directly from the study's public registry record.

Talk to the study team

Christin B. Destefano, MD, Lt Col, MC, USAF  ·  (301) 295-3190  ·  christin.destefano@usuhs.edu

W. Grant Day, MD, LCDR, MC, USN  ·  (757) 953-2194  ·  william.g.day26.mil@health.mil

Always discuss trial participation with your own doctor first.

Locations (3)

Uniformed Services University of the Health SciencesBethesda, Maryland, United StatesActive Not Recruiting
Walter Reed National Military Medical CenterBethesda, Maryland, United StatesRecruiting
Naval Medical Center PortsmouthPortsmouth, Virginia, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT07652580