Condition: Depressive Disorders · End-stage Chronic Kidney Disease Treated With Hemodialysis · Sponsor: Centre Hospitalier Annecy Genevois
Hemodialysis is a vital replacement therapy for patients with end-stage chronic kidney disease, but it imposes a heavy, demanding, and prolonged management, associated with a significant deterioration in quality of life. Hemodialysis patients are exposed to numerous physical, organizational, and social constraints, including repeated and prolonged sessions at the center, dietary and fluid restrictions, chronic fatigue, and frequent comorbidities. Therefore, depressive disorders in hemodialysis patients represent a major public health issue. The literature reports a high prevalence of depressive symptoms among hemodialysis patients, ranging from 22% to 60%, significantly higher than that observed in the general population. These disorders are associated with a significant deterioration in quality of life, increased hospitalizations, lower therapeutic adherence, an increased risk of suicide, and excess mortality. Despite these important clinical consequences, depressive disorders often remain underdiagnosed in hemodialysis. Current guidelines, including those from the Haute Autorité de Santé (HAS), emphasize the importance of regular quality of life assessments in patients with chronic kidney disease and recommend the use of validated questionnaires. However, they do not formalize a specific operational strategy for screening depressive disorders in routine hemodialysis practice, contributing to their under-evaluation. The gold standard diagnosis of depressive disorders reli…
This description comes directly from the study's public registry record.
Alexandra Rippoz · 0033 4 85522120 · arippoz@ch-annecygenevois.fr
DRCI CH Annecy Genevois · drci.promotion@ch-annecygenevois.fr
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| Centre Hospitalier Annecy Genevois | Annecy, France | Recruiting |
| Centre Hospitalier Métropole Savoie | Chambéry, France | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07651436