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Study identifier: NCT07649525 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Personalising Treatment for Myeloma Patients Based on Initial Response to NHS Treatment and Their Overall Fitness Level

Condition: Multiple Myeloma (MM) · Plasma Cell Leukemia (PCL)  ·  Sponsor: University of Leeds

PhasePhase 3
Planned participants1226
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

iFIT is a trial for newly diagnosed transplant-ineligible patients with the bone marrow cancer myeloma. These patients are generally older and have a lower level of fitness than others. Patients can take part if their doctor would otherwise recommend the standard NHS treatment daratumumab, lenalidomide and dexamethasone (DRd). After six months of DRd, the subsequent treatment a patient receives in iFIT is based on two factors: the patient's fitness level and treatment response. The trial compares different treatment strategies to determine whether outcomes can be improved for specific patient groups.

This description comes directly from the study's public registry record.

Talk to the study team

Emma McNaught  ·  0113 343 1978  ·  ctru-ifit@leeds.ac.uk

Catherine Olivier  ·  ctru-ifit@leeds.ac.uk

Always discuss trial participation with your own doctor first.

Locations (5)

Bristol Haematology and Oncology CentreBristol, United KingdomNot Yet Recruiting
Eastbourne District General HospitalEastbourne, United KingdomNot Yet Recruiting
St James University HospitalLeeds, United KingdomNot Yet Recruiting
The Clatterbridge Cancer Centre - LiverpoolLiverpool, United KingdomRecruiting
The Royal Marsden HospitalLondon, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07649525