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Study identifier: NCT07648693 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of the Safety and Effectiveness of CHORDS® Cerebral Protection System During TAVR: DUET Trial

Condition: Transcatheter Aortic Valve Replacement (TAVR) · Cerebral Vascular Accident (CVA)/Stroke  ·  Sponsor: Resonova (Shanghai) Medtech Limited

PhaseNA
Planned participants240
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective, multi-center, randomized controlled study. The goal of the study is to assess the safety and effectiveness of the Resonova® CHORDS® Cerebral Protection System in capturing and removing embolic debris during Transcatheter Aortic Valve Replacement (TAVR). A total of 240 eligible participants will be enrolled and randomized in a 1:1 ratio to undergo TAVR either with the CHORDS® Cerebral Protection System (Test group) or the Sentinel System (Control group).All the participants will be followed up at 30 days and 90 days post-procedure.

This description comes directly from the study's public registry record.

Talk to the study team

XU  ·  021-50206611  ·  j.xu@resonmed.com

Always discuss trial participation with your own doctor first.

Locations (15)

The First Affiliated Hospital of Bengbu Medical CollegeBengbu, Anhui, ChinaRecruiting
Anhui Provincial HospitalHefei, Anhui, ChinaRecruiting
Beijing Anzhen Hospital, Capital Medical UniversityBeijing, Beijing Municipality, ChinaRecruiting
The First Affiliated Hospital of the Army Medical University of the Chinese People's Liberation ArmyChongqing, Chongqing Municipality, ChinaRecruiting
Fujian Medical University Union HospitalFuzhou, Fujian, ChinaRecruiting
The First Affiliated Hospital of Fujian Medical UniversityFuzhou, Fujian, ChinaNot Yet Recruiting
Guangdong Provincial People's HospitalGuangzhou, Guangdong, ChinaRecruiting
Southern Medical University Nanfang HospitalGuangzhou, Guangdong, ChinaRecruiting
Sun Yat-sen Memorial Hospital of Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
The First Affiliated Hospital of Nanchang UniversityNanchang, Jiangxi, ChinaRecruiting
Qingdao University Affiliated HospitalQingdao, Shandong, ChinaRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07648693