Condition: Advanced Cancer · Sponsor: University Health Network, Toronto
This is a single-arm prospective, feasibility study evaluating the intravenous contrast-enhanced cone beam computed tomography (IV CBCT) for image guidance during radiotherapy. Patients treated with SFRT will receive IV-contrast enhanced CT and fMRI before treatment for simulation purposes. Additionally, patients will receive mpMRI just before and IV-contrast enhanced CBCT during their second and last fraction of RT, in addition to the standard of care CBCT that is acquired for daily image-guided patient positioning. Patients will undergo both IV-contrast enhanced CBCT and treatment on the TrueBeam with HyperSight imaging capability. We hypothesize IV contrast enhanced CBCT is feasible, well-tolerated by patients and improves the visibility of the target.
This description comes directly from the study's public registry record.
Jelena Lukovic, MD FRCPC MPH MRMD · 4169464501 · jelena.lukovic@uhn.ca
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| Princess Margaret Cancer Center | Toronto, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07648160