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Study identifier: NCT07647380 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TIS for Improving Cognitive Impairment in Schizophrenia

Condition: Schizophrenia Disorder · Cognitive Impairments  ·  Sponsor: Central South University

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

This study aims to evaluate the efficacy, safety, and underlying neural mechanisms of TIS targeting the hippocampus in ameliorating cognitive impairment associated with schizophrenia (CIAS). Researchers will compare active TIS to a sham control to see if TIS works to treat CIAS. Participants will receive TIS twice a day for 2 weeks. Their clinical data, including the baseline clinical symptom scale score, cognitive function, E/I imbalance index recorded by EEG, and MRI data, will be collected at baseline, at the end of the 2-week intervention, and 4 weeks after the intervention.

This description comes directly from the study's public registry record.

Talk to the study team

Renrong Wu  ·  15874179855  ·  wurenrong@csu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Second Xiangya Hospital, Central South UniversityChangsha, Hunan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07647380