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Study identifier: NCT07647328 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

Condition: ER-Positive HER2-Negative Breast Cancer  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants150
Who can joinAll sexes, 18 Years to 130 Years
Healthy volunteersNo

About this study

The purpose of this study is to investigate the efficacy, safety, and tolerability of camizestrant in combination with ribociclib in patients with ER+ HER2- BC who have not received any other systemic treatment for advanced disease. Participants will be treated within the trial until they discontinue the study treatment for any reason.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (84)

Research SiteDuarte, California, United StatesNot Yet Recruiting
Research SitePalo Alto, California, United StatesNot Yet Recruiting
Research SiteMarietta, Georgia, United StatesNot Yet Recruiting
Research SiteEvanston, Illinois, United StatesNot Yet Recruiting
Research SiteEdgewood, Kentucky, United StatesNot Yet Recruiting
Research SiteLouisville, Kentucky, United StatesNot Yet Recruiting
Research SiteReno, Nevada, United StatesNot Yet Recruiting
Research SiteSioux Falls, South Dakota, United StatesNot Yet Recruiting
Research SiteNashville, Tennessee, United StatesNot Yet Recruiting
Research SiteFort Worth, Texas, United StatesNot Yet Recruiting
Research SiteKingwood, Texas, United StatesRecruiting
Research SiteMidlothian, Virginia, United StatesNot Yet Recruiting

+ 72 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07647328