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Study identifier: NCT07646587 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)

Condition: COPD (Chronic Obstructive Pulmonary Disease)  ·  Sponsor: Windward Bio

PhasePhase 2
Planned participants105
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate - severe chronic obstructive pulmonary disease (COPD). WIN378 blocks the action of a protein called TSLP that causes inflammation in the lung and may contribute to COPD control and symptoms. The study will test how doses of WIN378 are handled by the body (pharmacokinetics) and assess the safety of the medicine and markers of COPD inflammation in exhaled breath and blood, lung function and COPD control (pharmacodynamics)

This description comes directly from the study's public registry record.

Talk to the study team

Juliana Hutchinson, MSc  ·  +4161 551 75 75  ·  clinical.trial.enquiry@windwardbio.com

Always discuss trial participation with your own doctor first.

Locations (4)

WB Contracted Clinical Research SiteMiami Lakes, Florida, United StatesRecruiting
WB Contracted Clinical Research SiteNorth Dartmouth, Massachusetts, United StatesRecruiting
WB Contracted Clinical Research SiteCharlotte, North Carolina, United StatesRecruiting
WB Contracted Clinical Research SiteMcKinney, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07646587