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Study identifier: NCT07644117 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Individualizing Anti-TNF Therapy in Patients With Inflammatory Bowel Disease

Condition: IBD (Inflammatory Bowel Disease) · Crohn Disease (CD) · Ulcerative Colitis (UC)  ·  Sponsor: Shmuel Kivity, MD

PhaseN/A
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This observational study aims to identify genes that may affect how patients with inflammatory bowel disease respond to anti-TNF treatment and why some patients lose response to treatment over time. The study will examine whether genetic markers can help predict which patients are more likely to respond to anti-TNF therapy. Participants who have not previously received anti-TNF treatment and are about to start advanced therapy will provide a blood sample to test for the genetic markers. Participants will also undergo regular assessments of current treatment, disease activity, and inflammatory markers during follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Rony Izhar, PhD  ·  +97237772613  ·  ronyi@tlvmc.gov.il

Ayal Hirsch, MD  ·  +972535289492  ·  ayalh@tlvmc.gov.il

Always discuss trial participation with your own doctor first.

Locations (1)

Dep. of Gastroenterology, Tel Aviv Sourasky Medical CenterTel Aviv, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT07644117