Condition: HIV -1 Infection · Antiretroviral Therapy · Drug Resistance, Microbial · Sponsor: Chinese University of Hong Kong
The study aims to determine the prevalence of drug resistance mutation (DRM) in virally suppressed HIV infection, and the impacts of regimen change and the presence of low level viremia. Adults living with HIV infection on antiretroviral therapy (ART) with full viral suppression would be recruited. Cases are patients planning for regimen switch, while controls are those with and without low level viraemia (LLV) not planned for switch. Blood samples would be collected before and after switch. Sequencing would be performed to identify DRM present in HIV-1 proviral DNA.
This description comes directly from the study's public registry record.
Shui Shan Lee, MD · +852 22528812 · sslee@cuhk.edu.hk
Ngai Sze Wong, PhD · +852 22528862 · candy_wong@cuhk.edu.hk
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| S.H. Ho Research Centre for Infectious Diseases, The Chinese University of Hong Kong | Hong Kong, Hong Kong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07643948