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Study identifier: NCT07643896 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment

Condition: Pregnant Individuals · Aneuploidy · Down Syndrome (Trisomy 21)  ·  Sponsor: BillionToOne Inc.

PhaseN/A
Planned participants1000
Who can joinFemale, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of the ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) study is to compare the concordance of results of a novel non-invasive circulating fetal cell (CFC) assay to the results of prenatal invasive diagnostic testing or postnatal genetic and clinical diagnosis of the resulting neonate. This is a prospective study of pregnant individuals.

This description comes directly from the study's public registry record.

Talk to the study team

Shannon O'Rourke Senior Research Manager, MS, CGC  ·  650-460-2551  ·  unityregistry@billiontoone.com

Always discuss trial participation with your own doctor first.

Locations (6)

Valley Perinatal ServicesPhoenix, Arizona, United StatesRecruiting
San Gabriel Valley Perinatal Medical GroupWest Covina, California, United StatesRecruiting
Sarasota Memorial Health Care SystemSarasota, Florida, United StatesRecruiting
Pediatrix Medical Group of GeorgiaAtlanta, Georgia, United StatesRecruiting
Woman's HospitalBaton Rouge, Louisiana, United StatesRecruiting
Pediatrix Medical GroupHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07643896