Condition: Neovascular Age-Related Macular Degeneration (nAMD) · Sponsor: Peking University People's Hospital
The goal of this observational study is to explore the effectiveness of aflibercept 8 mg in treating both treatment-naive and previously treated patients with neovascular age-related macular degeneration (nAMD) in a real-world setting. The main questions it aims to answer are: What are the short-term and long-term efficacy outcomes of aflibercept 8 mg in treatment-naive or previously treated nAMD patients? What are the safety characteristics and the treatment patterns of aflibercept 8 mg in these patient populations? Participants will: Receive aflibercept 8 mg as part of their clinical treatment for nAMD. Undergo assessments to evaluate both the efficacy and safety of the treatment over the short and long term. Provide data on their visual acuity (BCVA) changes at multiple follow-up points (4 weeks, 8 weeks, 16 weeks, 6 months, and 12 months). Report any adverse events and treatment patterns during the study period. Have their central subfield thickness (CST) measured at specified intervals. This study will help inform clinical practices regarding the use of aflibercept in nAMD patients and contribute to understanding its effectiveness and safety in real-world settings.
This description comes directly from the study's public registry record.
Mingwei Zhao · +86 13801057408 · dr_zhaomingwei@163.com
Always discuss trial participation with your own doctor first.
| Peking University People's Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Beijing CHAO-YANG Hospital, Capital Medical University | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Beijing Friendship Hospital, Capital Medical University | Beijing, Beijing Municipality, China | Recruiting |
| Beijing Haidian Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Peking Union Medical College Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Peking University First Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Peking University Third Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| The First Affiliated Hospital Of Fujian Medical University | Fuzhou, Fujian, China | Not Yet Recruiting |
| Shenzhen Eye Hospital | Shenzhen, Guangdong, China | Not Yet Recruiting |
| Affiliated Hospital Of Zunyi Medical University | Zunyi, Guizhou, China | Not Yet Recruiting |
| The 2nd Affiliated Hospital of Harbin Medical University | Harbin, Heilongjiang, China | Not Yet Recruiting |
| Nanyang Eye Hospital | Nanyang, Henan, China | Recruiting |
+ 15 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07640997