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Study identifier: NCT07638436 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

Condition: Esophageal Squamous Cell Carcinoma (ESCC)  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants42
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This clinical trial aims to preliminarily evaluate the efficacy and safety of adebrelimab combined with albumin-bound paclitaxel and carboplatin as neoadjuvant therapy for borderline resectable locally advanced esophageal squamous cell carcinoma (ESCC). The primary research objectives are to increase the R0 resection rate in such patients, thereby reducing the recurrence rate and improving overall survival (OS), as well as avoiding adverse reactions associated with radiotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Hong Yang, MD, PhD  ·  86-13560405144  ·  yanghong@sysucc.org.cn

Chief physician  ·  86-13560405144

Always discuss trial participation with your own doctor first.

Locations (1)

No. 651 Dongfeng East Road, GuangzhouGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07638436