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Study identifier: NCT07638046 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias

Condition: Older Adults With Elevated Dementia Risk  ·  Sponsor: University of South Carolina

PhasePhase 2
Planned participants54
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersYes

About this study

Mindful walking is a promising and practical strategy because it combines two activities known to support healthy aging: walking and mindfulness. Unlike many structured exercise programs, mindful walking is low intensity, accessible, and easier to sustain in daily life. It may be especially useful for older adults at elevated risk for ADRD. However, most existing mindful walking studies have focused on mental health outcomes, such as stress reduction, rather than cognitive health. Little is known about whether mindful walking can support cognition or how it may influence brain function. To address this gap and strengthen a future R01 resubmission, the investigators propose a two-arm randomized controlled pilot trial using functional near-infrared spectroscopy (fNIRS), a safe, non-invasive brain imaging method. fNIRS measures brain activity through sensors placed on the scalp and is well-suited for repeated assessments in older adults because it is quiet, portable, painless, and cost-effective. The investigators will recruit racially and ethnically diverse middle-aged and older adults from the Midlands of South Carolina who are at elevated risk for ADRD. Participants will be randomly assigned to one of two groups: mindful walking or walking-only control. Both groups will complete 8 staff-supervised individual sessions over 4 weeks. The mindful walking group will learn and practice simple mindfulness skills while walking in multiple settings, including lab-based, indoor, and ou…

This description comes directly from the study's public registry record.

Talk to the study team

Halle Prine, MS  ·  8039997392  ·  HPRINE@email.sc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of South CarolinaColumbia, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07638046